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Cat diagnosis and prevention of infectious peritonitis

Cats with central nervous system and eye symptoms; a small number of sick cats are granulomatous peritonitis ascites. In addition, some types can be developed into granulomatous exudative. However, both have shown chronic peritonitis, volatility of fever, lack of appetite and loss of weight. And the progression of exudative peritonitis fast than granulomatous peritonitis. FIPV also has been reported to cause acute, purulent inflammation and necrosis of the testis. In addition, the disease can still result in pregnancy cat miscarriage,[link widoczny dla zalogowanych], stillbirth, newborn death or cat before and after weaning. 4 diagnosis based on epidemiological characteristics, clinical symptoms, pathological changes and laboratory tests can make a preliminary diagnosis, after FIPV infection. Phase proteins in serum (haptoglobin, serum amyloid A, a one acid glycoprotein, IgG, IgM) concentrations. . FIP typical exudative pleural and peritoneal effusion, effusion was yellow, thick, high protein content, prone to foam when shaken,[link widoczny dla zalogowanych], standing solidification can occur, with moderate amount of macrophages and neutrophils and other inflammatory cell. With central nervous system and eye disease risk cats, in the cerebrospinal fluid and aqueous humor fluid, protein content increased. Serological diagnosis must rely on testing and virus isolation. DanielleA. Gunn-Moore, etc. by reverse transcription polymerase chain reaction detection of FCoV genomes found in serum can detect the virus and whether the positive health status has nothing to do with the cat. Illustrate the application of this method of diagnosis is not unique. FIPV can only be used as diagnostic aids. 5 Control of the disease has not currently practical and reliable method of treatment. Can only be used to support therapy,[link widoczny dla zalogowanych], application of the role of suppression of the immune and anti-inflammatory drugs, such as the combination of interferon and glucocorticoids cats, and to give supplementary infusion to correct the dehydration, the use of antibiotics to prevent secondary infection while using antiviral drugs,[link widoczny dla zalogowanych], thoracentesis to relieve respiratory symptoms, but these treatments can prolong the lives of sick cats, can not cure the disease. More than 6 years old on the obvious effect of a cat. Once the typical symptoms, the majority of poor prognosis. So far, no effective vaccine for the prevention and treatment of this disease, the use of conventional vaccines and recombinant vaccines ineffective, mainly because of FIPV infection is dependent increase of the phenomenon, that is, the body in the FIP sick cats. Antibody and virus binding. And macrophages through the Fc receptor binding for the virus to be eaten in macrophages; the same time involving the complement system was activated, blood coagulation, cytokine release, leading to peritonitis and fluid leakage. Recently found, by the preparation of serum type �� DF2 strain of temperature-sensitive mutant, by intranasal inoculation, could induce a strong local mucosal immunity and cellular immunity, and did not induce antibody-dependent enhancement. To prevent the occurrence of this disease have a certain effect, the proposed application of the cat over 4 months ~. At the same time. Should eliminate blood-sucking insects (such as lice, mosquitoes, flies, etc.) and rats, prevent the spread of the virus. Sick cats and infected cats are the source of infection of this disease. Stress to avoid contact with them healthy cats. And make environmental disinfection and cleaning, reduce environmental waste and other pollution sources in the chance of infection.

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