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Hydroxyethyl starch on blood rheology of Clinical Research

s) compared with before treatment ※ P <0.05, ※ ※ P <0.01; compared with the equilibrium liquid △ P <0.05, △ △ P <0.0l 』research support the work of such Kiesewetter, HE Sri Lanka through the blood-thinning, reduce blood viscosity, improve blood rheology properties, thereby improving tissue perfusion and oxygenation. Boldt 』applications such as laser Doppler flowmetry (LDF) monitoring of patients with forearm and forehead skin blood flow, hydroxyethyl starch proved to be effective in improving microcirculation status. Goto dextran compared to 70, dextran, improved thermal degradation of gelatin (MT-ge1) and hydroxyethyl starch (I-IES0.55) 4 种 plasma substitutes on hemorheology. The results showed that: hydroxyethyl starch and dextran-4o to increase red blood cell surface loading and maintaining the suspension stability of blood, red blood cells to reduce the formation of cord-like money. Particularly in the case of low shear rate, hydroxyethyl starch on reducing blood viscosity, improve microcirculation blood flow better than the several other colloidal 』. Our tests confirmed that hydroxyethyl starch - HES significantly reduced red blood cell aggregation, reduce sedimentation equation K value, reducing the low shear whole blood viscosity, so that between the aggregation of red blood cells weaken, therefore, have to reduce red blood cell HES The fetal umbilical artery resistance and maternal hemorheology positive correlation J, so the improvement of hemorheology in patients with cesarean section will help the placenta blood, is conducive to fetal circulation, improve fetal oxygen delivery. In this study there was no red blood cell deformability, erythrocyte rigidity index of significant change, indicating that HES does not change the red blood cell deformability, which is different from the type of gelatin plasma substitute blood Ting Jing (Gelofusine), because the safety of blood given to increase red blood cell deformability, reduced red blood cell deformability, so that red blood cells easily spleen reticular system, seizure and destruction, leading to shortened red cell life 』. Due to the low shear rate blood viscosity produced mainly by the red blood cell aggregation and high shear rate blood viscosity determined mainly by the red blood cell deformability, so our results suggest: He Siming significantly reduced red blood cell aggregation at the same time, do not deformability of red blood cells, in terms of improving the hemorheology of HES may be superior to blood safety. In conclusion, HES in patients undergoing cesarean section improved rheology function better than crystalloid - fluid balance. Caesarean section in patients with appropriate application of colloid - HES will help to improve blood rheology, thus improving microcirculation.

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